AVIEWOFPAST,CURRENT,ANDFUTURESTUDIESINCRYOBIOLOGYANDFERTILITY PRESERVATION

Abstract

For many years, cryopreservation has been used to preserve living biological specimens. The increased risks to
human fertility from diseases like cancer and their treatment protocols, such as radiation and chemotherapy, as
well as the general lifestyle trend toward later marriages, have led to its expansion into the field of fertility
preservation. New scientific methods, like cryostorage, which involves storing live cells and tissues at low
temperatures and reviving them when needed, have greatly benefited the use of assisted reproductive
techniques (ART) to preserve fertility. In order to create a future roadmap for this field, this review focuses on
"cryopreservation science monitoring in reproductive biomedicine" and assesses knowledge, trends, driving
forces, impetus, and emerging technologies. The importance of strategically planning cryobiology research to
support its wider use in therapeutics in the future is highlighted by our analysis of the field. Recognizing this
need, the Royan Institute in Tehran, Iran, has created a strategic plan to conduct interdisciplinary research on
the use of cryobiology, including cryobioengineering, in disease mitigation. We anticipate that this study will
contribute to an increase in the quantity and quality of expert knowledge and public discussion regarding
cryopreservation's role in fertility preservation within ART.