An unusual presentation of gastrointestinal stromal tumour arising from the Ileum and involving the urinary bladder

Abstract

Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors that typically originate from the stomach and
small intestines, though they can occasionally originate from unusual sites that do not involve the GI
(gastrointestinal) tract. Men between the ages of 60 and 65 are more likely to develop GISTs. Histology and IHC
(immunohistochemistry) are used to confirm the diagnosis of these tumors, which are rarely symptomatic and are
typically found accidentally on radiography or during surgery. This case illustrates an uncommon presentation in a
65-year-old man who complained of fatigue, rectal bleeding, and dysuria as a result of an underlying infraumbilical
tumor. The tumor was later identified as a GIST originating from the ileum and simultaneously affecting the
bladder, and it was successfully treated with neoadjuvant imatinib therapy and surgical resection.